Pulmonaryarterialhypertension相关论文
Preventive Effect and Mechanism of Ethyl Acetate Extract of Sceptridium ternatum in Monocrotaline-In
Objective:To observe the effect and molecular mechanism of ethyl acetate extract of Sceptridium tematum (STE) on the mon......
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Osthole attenuates pulmonary arterial hypertension by the regulation of sphingosine 1-phosphate in r
Osthole is observed to have the capacity to treat pulmonary arterial hypertension (PAH) in rats,but molecular mechanism ......
Noninvasive Prediction of Pulmonary Artery Pressure and Vascular Resistance by using Cardiac Magneti
Purpose: It is too invasive to achieve hemodynamic variables for pulmonary arterial hypertension (PAH) patients by using......
Diffuse Pulmonary Arteriovenous Fistulas with Pulmonary Arterial Hypertension:Case Report and Review
目的 Pulmonary arteriovenous fistulas (PAVFs) are rare.Diffuse type PAVFs with pulmonary arterial hypertension (PAH) are......
The Fuctional Characteristic of Mg2+and Solute Carrier Family 41 in Pulmonary Hypertension Rats Indu
Introduction: The vascular pathological states in pulmonary hypertension(PH)owe much to an acute homeostasis imbalance o......
Characteristics and Risk Factors of Pulmonary Arterial Hypertension in the Patients with Primary Sj(
Objective:Since 2007,PUMCH has initiated a single-center RHC-based PAH study in pSS.The baseline characteristics of thes......
Interruption of CD40 Pathway Improves Efficacy of Transplanted Endothelial Progenitor Cells in Monoc
Transplantation of endothelial progenitor cells (EPCs) plays a therapeutic role in pulmonary arterial hypertension (PAH)......
Norepinephrine acting on alpha1D-adreneroceptor promotes proliferation of pulmonary artery smooth mu
The abnormal proliferation of pulmonary artery smooth muscle cells(PASMCs)is an important pathophysiological process in ......
Objective: To investigate the effect of Osthole (Ost) on TGF-β1/Smad3 signaling pathway in pulmonary arterial hypertens......
PO051-The significance of antiphospholipid antibodies against some target antigens in SLE patients w
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Role of LOX-1 in pulmonary vascular remodeling in rats with hypoxia induced pulmonary arterial hyper
Aim:To investigate the role of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in pulmonary vascular rem......
PI3K/Akt pathway participates in the processes that TGF-β1 mediated the pulmonary vascular remodelin
Transforming growth factor-beta1 (TGF-β1), a multifunctional growth factor, is activated and increased under hypoxia co......
The clinical analysis of Interstial lung disease and pulmonary art erial hypertension Secondary to c
Objective:To investgate the clinic features of interstitial lung disease(ILD) and pulmonary arterial hypertension(PAH) s......
Circulating ghrelin was negatively correlated with pulmonary arterial pressure in atrial septal defe
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Background:Pulmonary artery remodeling induced by excessproliferation,migration and apoptosis resistance of pulmonar......
目的评价超声心动图预测先天性心脏病相关性肺动脉高压患者肺循环参数的临床价值。方法选择2011年3月至2014年3月收治的38例肺动脉......
目的:探索在野百合碱诱导的肺动脉高压大鼠模型中,实施经胸肺动脉去神经支配术改善肺动脉高压和肺动脉重构的效果.方法:将24只健康......
脑钠肽是心脏科临床一种重要的心肌标志物,其提取物也已应用于临床.肺动脉高压是指肺动脉压力超过25 mm Hg的病理状态,会引起右侧......
目的 通过拟合肺动脉高压(PAH)患者压力-容积环并计算相关参数,研究右心室-肺动脉耦合的相关机制.方法 纳入2015年1月至2015年12月......
目的 采用二维斑点追踪(2D-STE)技术评价系统性红斑狼疮(SLE)患者的右心房功能变化.方法 选取A组(对照组)为健康志愿者30例.根据患......
肺动脉高压是以肺小动脉的血管痉挛、内膜增生和重构为主要特征的一种疾病.它是一进展性疾病,生存期为2.8年,早期诊断和治疗干预是......
先天性心脏病相关肺动脉高压( PAH-CHD)是肺动脉高压中最常见的类型之一。合理选择PAH-CHD的治疗方案将直接影响患者预后。近年来,PAH......
肺动脉高压会导致患者右室功能减低,早诊断、早治疗肺动脉高压能明显改善患者的预后.近年来应用多普勒超声技术对肺动脉高压患者右......
肺动脉高压是以肺小动脉的血管痉挛、内膜增生、重构为主要特征的一种疾病.肺小动脉的血管增生、重构导致肺血管阻力进行性增加,最......
在过去的20年,由于小儿心脏外科和先天性心脏病介入治疗技术的发展,使得先天性心脏病患者的预后较过去明显改善,先天性心脏病合并......
铁代谢异常可能通过多种途径参与肺动脉高压的发生发展。目前研究发现铁缺乏、铁代谢紊乱普遍存在于特发性肺动脉高压和遗传性肺动......
肺动脉高压是一种高致死性恶性心血管疾病,临床表现为肺动脉压力进行性升高,导致患者血管重构、右心肥大、心功能衰竭甚至死亡.肺......
肺动脉高压是一种可以导致右心衰竭及死亡的危重病.肺动脉高压合并心包积液病死率高,但关于肺动脉高压合并心包积液的数据相当匮乏......
系统性硬化病相关肺动脉高压是结缔组织疾病相关肺动脉高压中最常见的一种类型,也是系统性硬化病的主要死亡原因,其病死率为特发性肺......
肺动脉高压是一组进展性的、预后极差的恶性心脏疾病,本病以肺血管重构,肺血管阻力升高,最终导致右心衰竭为特点。最近5年,随着对肺动......
RhoA与其下游的效应物ROCK相互作用,调控肺血管收缩、肺血管重构、血栓形成以及炎症反应等病理生理过程,参与肺动脉高压的形成与发......
目的 探讨影响系统性红斑狼疮合并肺动脉高压预后的相关冈素.方法 采用回顾性队列研究的策略,研究样本为1997年1月至2008年1月在中......
目的探讨心脏磁共振成像(CMRI)对肺动脉高压(PAH)患者右心室功能的评估价值。方法计算机检索美国国立医学图书馆MEDLINE、万方数据库及......
奥普力农是20世纪90年代在日本上市的新一代磷酸二酯酶Ⅲ(PDEⅢ)抑制剂,该药可增加心肌收缩力,减少外周血管阻力,但不影响血压和心率,目......
目的探讨核因子-κB(NF-κB)及其抑制剂吡咯烷二硫代氨基甲酸盐(PDTC)在野百合碱(MCT)所致肺动脉高压中的作用及其机制。方法大鼠......
目的 探讨过表达F92A-丙氨酸替代窖蛋白-1(Cav1)的大鼠骨髓间充质干细胞(rBMSCs/ F92A-Cav1)对肺动脉高压(PAH)大鼠的治疗作用及其......
Rhodiola crenulata extract decreases fatty acid oxidation and autophagy to ameliorate pulmonary arte
Pulmonary arterial hypertension (PAH) is a devastating pulmonary circulation disease lacking high-efficiency therapeutic......